To understand the origin of evil, you must go back to the beginning.
Former FBI Agent Will Graham, who was once almost killed by the savage Hannibal 'The Cannibal' Lecter, now has no choice but to face him again, as it seems Lecter is the only one who can help Graham track down a new serial killer.
Edward Norton Will Graham
Anthony Hopkins Hannibal Lecter
Ralph Fiennes Francis Dolarhyde
Emily Watson Reba McClane
Harvey Keitel Jack Crawford
Philip Seymour Hoffman Freddy Lounds
Anthony Heald Dr. Chilton
Mary-Louise Parker Molly Graham
Tyler Patrick Jones Josh Graham
Ken Leung Lloyd Bowman
Frankie Faison Barney
Lalo Schifrin Conductor
Tim Wheater Flautist
John Rubinstein Dinner Guest
David Doty Dinner Guest
Brenda Strong Dinner Guest
Robert Curtis Brown Dinner Guest
Mary Anne McGarry Dinner Guest
Marc Abraham Dinner Guest
Veronica De Laurentiis Dinner Guest
Michael Cavanaugh Forensic Dentist
Madison Mason Police Commissioner
Bill Duke Police Chief
Cliff Dorfman Cop
Phillip B. Fahey Cop
Tom Verica Charles Leeds
Marguerite MacIntyre Valerie Leeds
Thomas Curtis Billy Leeds
Azura Skye Bookseller
Jeanine Jackson Dr. Hassler
William Lucking Byron Metcalf
Katie Rich Woman Detective
Alex Berliner Photographer
Ellen Burstyn Grandma Dolarhyde (voice) (uncredited)
Mary Beth Hurt Museum Curator (uncredited)
James Pickens Jr. Male Zoo Doctor (uncredited)
Frank Whaley Ralph Mandy (uncredited)
Tanya Newbould Chromalux Secretary
Elizabeth Dennehy Beverly
Joseph Simmons Janitor
Mark Moses Father in Video
Norman Fessler Driver (uncredited)
Alex D. Linz Young Dolarhyde (voice)
Jordan Gruber Sean Leeds
Morgan Gruber Susie Leeds
Richard Pelzman Locksmith
Andreana Weiner Dr. Bloom's Secretary
Stanley Anderson Jimmy
Terence Rowley Superintendent
Gianni Russo Newsie
Al Brown Tattler Guard
Edward Nickerson FBI Agent
Kyra Helfrich Child in Video
Frank Bruynbroek Chef
Dwier Brown Mr. Jacobi
Grace Stephens Jacobi Child
Lucy Stephens Jacobi Child
Kevin Bashor Jacobi Child
Hillary Straney Museum Secretary
Christopher Curry Mr. Fisk
Conrad E. Palmisano Deputy in Car
Tony Reynolds FBI Agent
- Edward NortonWill Graham
- Anthony HopkinsHannibal Lecter
- Ralph FiennesFrancis Dolarhyde
- Emily WatsonReba McClane
- Harvey KeitelJack Crawford
- Philip Seymour HoffmanFreddy Lounds
- Anthony HealdDr. Chilton
- Mary-Louise ParkerMolly Graham
- Tyler Patrick JonesJosh Graham
- Ken LeungLloyd Bowman
- Frankie FaisonBarney
- Lalo SchifrinConductor
- Tim WheaterFlautist
- John RubinsteinDinner Guest
- David DotyDinner Guest
- Brenda StrongDinner Guest
- Robert Curtis BrownDinner Guest
- Mary Anne McGarryDinner Guest
- Marc AbrahamDinner Guest
- Veronica De LaurentiisDinner Guest
- Michael CavanaughForensic Dentist
- Madison MasonPolice Commissioner
- Bill DukePolice Chief
- Cliff DorfmanCop
- Phillip B. FaheyCop
- Tom VericaCharles Leeds
- Marguerite MacIntyreValerie Leeds
- Thomas CurtisBilly Leeds
- Azura SkyeBookseller
- Jeanine JacksonDr. Hassler
- William LuckingByron Metcalf
- Katie RichWoman Detective
- Alex BerlinerPhotographer
- Ellen BurstynGrandma Dolarhyde (voice) (uncredited)
- Mary Beth HurtMuseum Curator (uncredited)
- James Pickens Jr.Male Zoo Doctor (uncredited)
- Frank WhaleyRalph Mandy (uncredited)
- Tanya NewbouldChromalux Secretary
- Elizabeth DennehyBeverly
- Joseph SimmonsJanitor
- Mark MosesFather in Video
- Norman FesslerDriver (uncredited)
- Alex D. LinzYoung Dolarhyde (voice)
- Jordan GruberSean Leeds
- Morgan GruberSusie Leeds
- Richard PelzmanLocksmith
- Andreana WeinerDr. Bloom's Secretary
- Stanley AndersonJimmy
- Terence RowleySuperintendent
- Gianni RussoNewsie
- Al BrownTattler Guard
- Edward NickersonFBI Agent
- Kyra HelfrichChild in Video
- Frank BruynbroekChef
- Dwier BrownMr. Jacobi
- Grace StephensJacobi Child
- Lucy StephensJacobi Child
- Kevin BashorJacobi Child
- Hillary StraneyMuseum Secretary
- Christopher CurryMr. Fisk
- Conrad E. PalmisanoDeputy in Car
- Tony ReynoldsFBI Agent